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Pellman Lab - Cell Division and Genome Instability

Pellman Lab - Cell Division and Genome Instability

Picture

Archana Krishnamoorthy
​
[email protected]​

EDUCATION
PhD, Biochemistry, Vanderbilt University, Nashville, TN, USA

MS, Biology, Middle Tennessee State University, TN, USA
​
Bachelor of Engineering, Biotechnology, PES Institute of Technology, Bangalore, India

AWARDS & HONORS
Damon Runyon Fellowship Award
​Selected Publications:

Mehta K, Thada V, Zhao R, Krishnamoorthy A, Leser M, Lindsey Rose K, Cortez D. (2022). CHK1 phosphorylates PRIMPOL to promote replication stress tolerance. Science Advances. Apr;8(13):eabm0314. DOI: 10.1126/sciadv.abm0314. PMCID: PMC8967226

Krishnamoorthy A, Jackson J, Mohamed TA, Adolph M, Vindigni A, Cortez D. (2021). RADX prevents genome instability by confining replication fork reversal to stalled forks. Molecular Cell. DOI: 10.1016/j.molcel.2021.05.014.
Featured in issue

Liu W, Krishnamoorthy A, Zhao R, Cortez D. (2020). Two replication fork remodeling pathways generate nuclease substrates for distinct fork protection factors. Science Advances. 6(46):eabc3598. DOI: 10.1126/sciadv.abc3598.

Bhat KP, Krishnamoorthy A, Dungrawala H, Garcin EB, Modesti M, Cortez D. (2018). RADX modulates RAD51 activity to control replication fork protection. Cell Reports. 24(3):538-545. DOI: 10.1016/j.celrep.2018.06.061.

Krishnamoorthy A, Robertson JB. (2015). Dual-color monitoring overcomes the limitations of single bioluminescent reporters in fast-growing microbes and reveals phase-dependent protein productivity during the metabolic rhythms of Saccharomyces cerevisiae. Applied Environmental Microbiology 81:6484-6495. DOI:10.1128/AEM.01631-15.
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