Mitchell Leibowitz
MitchellL_Leibowitz@dfci.harvard.edu

EDUCATION
PhD, Biological and Biomedical Sciences, Harvard University, Cambridge, MA, USA
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BS, Chemistry with specialization in biochemistry; Biology, University of Virginia, Virginia, USA​

​AWARDS AND HONORS
​National Science Foundation Graduate Research Fellowship (2013)

SELECTED PUBLICATIONS
Leibowitz, ML*, Papathanasiou, S*, Doerfler, P, Blaine, LJ, Sun L, Yao, Y, Zhang, CZ, Weiss, MJ, Pellman, D. Chromothripsis as an on-target consequences of CRISPR-Cas9 genome editing. Nat. Genet. 53: 895-905 (2021).
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​Leibowitz, ML*, Zhang, CZ*, Pellman, D. Chromothripsis: A new mechanism for rapid karyotype evolution. Annu. Rev. Genet. 49: 183-211 (2015).

Zhang, CZ*, Leibowitz, ML*, Pellman, D. Chromothripsis and beyond: rapid genome evolution from complex chromosomal rearrangements. Genes & Development. 27: 2513-2530 (2014).

Malhotra, A, Lindberg, M, Faust, GG, Leibowitz, ML, Clark, RA, Layer RM, Quinlan, AR, Hall, IM. Breakpoint profiling of 64 cancer genomes reveals numerous complex rearrangements spawned by homology-independent mechanisms. Genome Res 23: 762-776 (2013).

Quinlan, AR, Boland MJ, Leibowitz, ML, Shumilina, S, Pehrson, SM, Baldwin, KK, Hall, IM. Genome sequencing of mouse induced pluripotent stem cells reveals retroelement stability and infrequent DNA rearrangement during reprogramming. Cell Stem Cell 9: 366-373 (2011).

​Quinlan, AR, Clark, RA, Sokolova, S, Leibowitz, ML, Zhang, Y, Hurles, ME, Mell, JC, Hall, IM. Genome-wide mapping and assembly of structural variant breakpoints in the mouse genome. Genome Res 20: 623-635 (2010).